Alec C Kimmelman Selected Research

bis- 2- (5- phenylacetamido- 1,2,4- thiadiazol- 2- yl)ethyl sulfide

1/2018

Glutamine metabolism via glutaminase 1 in autosomal-dominant polycystic kidney disease.

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Alec C Kimmelman Research Topics

Disease

38	Neoplasms (Cancer) 10/2023 - 10/2007
23	Pancreatic Neoplasms (Pancreatic Cancer) 10/2023 - 12/2008
18	Adenocarcinoma 10/2023 - 07/2011
3	Lung Neoplasms (Lung Cancer) 04/2020 - 12/2014
2	Inflammation (Inflammations) 04/2024 - 01/2016
2	Fibrosis (Cirrhosis) 01/2022 - 10/2020
2	Autosomal Dominant Polycystic Kidney (ADPKD) 10/2020 - 01/2018
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2016 - 12/2014
2	Multiple Myeloma 05/2015 - 06/2014
2	Glioblastoma (Glioblastoma Multiforme) 10/2007 - 06/2004
1	Mitochondrial Diseases (Mitochondrial Disease) 06/2023
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Triple Negative Breast Neoplasms 01/2021
1	Hypoxia (Hypoxemia) 10/2020
1	Colorectal Neoplasms (Colorectal Cancer) 01/2020
1	Anemia 01/2019
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2018
1	Cysts 01/2018
1	Starvation 01/2016
1	Pancreatitis 01/2016
1	Residual Neoplasm 05/2015
1	Sarcoma (Soft Tissue Sarcoma) 01/2015
1	Leukemia 06/2014
1	Lymphopenia (Lymphocytopenia) 06/2014
1	Lymphoma (Lymphomas) 06/2014
1	Hematologic Neoplasms (Hematological Malignancy) 06/2014

Drug/Important Bio-Agent (IBA)

8	Glutamine (L-Glutamine)FDA Link 10/2023 - 04/2013
5	Proteins (Proteins, Gene)FDA Link 06/2023 - 05/2014
5	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2019 - 12/2011
5	Phosphotransferases (Kinase)IBA 01/2018 - 10/2007
3	IronIBA 06/2023 - 01/2019
3	Transaminases (Aminotransferases)IBA 01/2020 - 01/2018
3	Glutamic Acid (Glutamate)FDA Link 01/2020 - 01/2018
3	Oxaloacetic Acid (Oxalacetic Acid)IBA 01/2020 - 01/2018
3	Chloroquine (Aralen)FDA LinkGeneric 09/2014 - 04/2011
2	Interleukin-6 (Interleukin 6)IBA 06/2023 - 01/2016
2	Adenosine Triphosphate (ATP)IBA 06/2023 - 01/2018
2	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 01/2018
2	CollagenIBA 01/2022 - 01/2018
2	Amino Acids FDA Link 01/2022 - 10/2021
2	Cysteine (L-Cysteine)FDA Link 01/2021 - 01/2021
2	EnzymesIBA 01/2021 - 11/2018
2	GlutaminaseIBA 10/2020 - 01/2018
2	CarbonIBA 01/2020 - 01/2016
2	Alanine (L-Alanine)FDA Link 01/2020 - 01/2016
2	Antineoplastic Agents (Antineoplastics)IBA 01/2019 - 01/2016
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 11/2018 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 02/2014 - 04/2012
1	Small Cytoplasmic RNAIBA 04/2024
1	RNA (Ribonucleic Acid)IBA 04/2024
1	ProdrugsIBA 10/2023
1	Ammonium Chloride (Sal Ammoniac)FDA Link 06/2023
1	metal transporting protein 1 (ferroportin)IBA 06/2023
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 06/2023
1	SulfurIBA 06/2023
1	Leucovorin (Folinic Acid)FDA Link 10/2022
1	Fluorouracil (Carac)FDA LinkGeneric 10/2022
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 10/2022
1	Irinotecan (Camptosar)FDA LinkGeneric 10/2022
1	folfirinoxIBA 10/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Mannose ReceptorIBA 01/2022
1	Arginine (L-Arginine)FDA Link 01/2022
1	Deubiquitinating EnzymesIBA 10/2021
1	coenzyme Q10 (CoQ10)IBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	Serine (L-Serine)FDA Link 11/2020
1	Codon (Codons)IBA 11/2020
1	Nerve Growth Factor (NGF)IBA 11/2020
1	larotrectinibIBA 11/2020
1	Oxygen (Dioxygen)IBA 10/2020
1	Doxycycline (Periostat)FDA LinkGeneric 01/2020
1	Immune Checkpoint InhibitorsIBA 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2020
1	Ferritins (Ferritin)IBA 01/2019
1	NucleotidesIBA 11/2018
1	CB-839IBA 01/2018
1	bis- 2- (5- phenylacetamido- 1,2,4- thiadiazol- 2- yl)ethyl sulfideIBA 01/2018
1	ColforsinIBA 01/2018
1	Protein Isoforms (Isoforms)IBA 01/2018
1	DNA-Activated Protein KinaseIBA 01/2018
1	Histones (Histone)IBA 01/2017
1	CeruletideIBA 01/2016
1	N- (cyanomethyl)- 4- (2- ((4- (4- morpholinyl)phenyl)amino)- 4- pyrimidinyl)benzamideIBA 01/2016
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2016
1	ChemokinesIBA 01/2016
1	Janus Kinase InhibitorsIBA 01/2016
1	Bortezomib (Velcade)FDA Link 05/2015
1	Melphalan (Alkeran)FDA LinkGeneric 05/2015
1	NADP (NADPH)IBA 01/2015
1	AntioxidantsIBA 01/2015
1	beta-lapachoneIBA 01/2015
1	Branched-Chain Amino AcidsIBA 10/2014
1	Alanine Transaminase (SGPT)IBA 06/2014

Therapy/Procedure

18	Therapeutics 10/2021 - 10/2007
3	Drug Therapy (Chemotherapy) 01/2023 - 04/2011
3	Radiotherapy 01/2020 - 01/2016
2	Image-Guided Radiotherapy 04/2020 - 12/2014
1	Precision Medicine 01/2022
1	Immunotherapy 01/2016